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Structural-function Discovery Laboratory

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Structural determinants for the stereoselective hydrolysis of chiral substrates by phosphotriesterase
  • AuthorPing-Chuan Tsai, Yubo Fan, Jungwook Kim, Lijiang Yang, Steven C. Almo, Yi Qin Gao, and Frank M. Raushel
  • Year2010
  • SourceBiochemistry. 2010 Sep 21;49(37):7988-97. doi: 10.1021/bi101058z

Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase
  • AuthorJungwook Kim, Ping-Chuan Tsai, Shi-Lu Chen, Fahmi Himo, Steven C. Almo, and Frank M. Raushel
  • Year2008
  • SourceBiochemistry. 2008 Sep 9;47(36):9497-504. doi: 10.1021/bi800971v

Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase
  • AuthorJungwook Kim, Vladimir Malashkevich, Setu Roday, Michael Lisbin, Vern L. Schramm, and Steven C. Almo
  • Year2006
  • SourceBiochemistry. 2006 May 23;45(20):6407-16. doi: 10.1021/bi0522394

Long-range allosteric transitions in carbamoyl phosphate synthetase
  • AuthorJames B. Thoden, Xinyi Huang, Jungwook Kim, Frank M. Raushel, and Hazel M Holden
  • Year2004
  • SourceProtein Sci. 2004 Sep;13(9):2398-405. doi: 10.1110/ps.04822704

Perforation of the tunnel wall in carbamoyl phosphate synthetase derails the passage of ammonia between sequential active sites
  • AuthorJungwook Kim, and Frank M. Raushel
  • Year2004
  • SourceBiochemistry. 2004 May 11;43(18):5334-40. doi: 10.1021/bi049945+

Access to the carbamate tunnel of carbamoyl phosphate synthetase
  • AuthorJungwook Kim, and Frank M. Raushel
  • Year2004
  • SourceArch Biochem Biophys. 2004 May 1;425(1):33-41. doi: 10.1016/j.abb.2004.02.031

The catalytic mechanism of galactose mutarotase
  • AuthorJames B. Thoden, Jungwook Kim, Frank M. Raushel, and Hazel M Holden
  • Year2003
  • SourceProtein Sci. 2003 May;12(5):1051-9. doi: 10.1110/ps.0243203

Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis
  • AuthorJames B. Thoden, Jungwook Kim, Frank M. Raushel, and Hazel M. Holden
  • Year2002
  • SourceJ Biol Chem . 2002 Nov 22;277(47):45458-65. doi: 10.1074/jbc.M208395200

Structural defects within the carbamate tunnel of carbamoyl phosphate synthetase
  • AuthorJungwook Kim, Stanley Howell, Xinyi Huang, and Frank M. Raushel
  • Year2002
  • SourceBiochemistry. 2002 Oct 22;41(42):12575-81. doi: 10.1021/bi020421o

Allosteric control of the oligomerization of carbamoyl phosphate synthetase from Escherichia coli.
  • AuthorJungwook Kim, and Frank M. Raushel
  • Year2001
  • SourceBiochemistry. 2001 Sep 18;40(37):11030-6. doi: 10.1021/bi011121u
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