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Structural-function Discovery Laboratory

  효소구조기능연구실

 Structure-Function Discovery Laboratory

Structures

Human PDK2 complexed with GM67520 이미지
Human PDK2 complexed with GM67520 PDB: 6LIO (Crystal structure of human PDK2 complexed with GM67520) Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds Author : Jihoon Kang, Haushabhau S. Pagire, Donguk Kang, Yo Han Song, In Kyu Lee, Kang Taek Lee, Chin-Ju Park, Jin Hee Ahn, and Jungwook Kim Biochem Biophys Res Commun. 2020 Jun 30;527(3):778-784. doi: 10.1016/j.bbrc.2020.04.102
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Human PDK2 complexed with GM10030 이미지
Human PDK2 complexed with GM10030 PDB: 6LIN (Crystal structure of human PDK2 complexed with GM10030) Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds Author : Jihoon Kang, Haushabhau S. Pagire, Donguk Kang, Yo Han Song, In Kyu Lee, Kang Taek Lee, Chin-Ju Park, Jin Hee Ahn, and Jungwook Kim Biochem Biophys Res Commun. 2020 Jun 30;527(3):778-784. doi: 10.1016/j.bbrc.2020.04.102
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Human PDK2 complexed with an allosteric inhibitor 이미지
Human PDK2 complexed with an allosteric inhibitor PDB: 6LIL (Crystal structure of human PDK2 complexed with an allosteric inhibitor compound 8c) Structural basis for the inhibition of PDK2 by novel ATP- and lipoyl-binding site targeting compounds Author : Jihoon Kang, Haushabhau S. Pagire, Donguk Kang, Yo Han Song, In Kyu Lee, Kang Taek Lee, Chin-Ju Park, Jin Hee Ahn, and Jungwook Kim Biochem Biophys Res Commun. 2020 Jun 30;527(3):778-784. doi: 10.1016/j.bbrc.2020.04.102
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Cofactor-bound Rv0187 from M. tuberculosis 이미지
Cofactor-bound Rv0187 from M. tuberculosis PDB: 6JCL (Crystal structure of cofactor-bound Rv0187 from MTB) Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis Sanghyun Lee, Jihoon Kang, and Jungwook Kim Sci Rep. 2019 May 30;9:8059. doi:10.1038/s41598-019-44592-7
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