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Structural-function Discovery Laboratory

  효소구조기능연구실

 Structure-Function Discovery Laboratory

Structures

PssA from E. coli in apo and complexed with 16:0/16:0 CDP-DG 이미지
PssA from E. coli in apo and complexed with 16:0/16:0 CDP-DG PDB: 8YR5 Crystal structure of E. coli phosphatidylserine synthase in apo state PDB: 8YR6 Crystal structure of E. coli phosphatidylserine synthase complexed with 16:0/16:0 CDP-DG Publication: Lee, E., Cho, G., & Kim, J. (2024). Structural basis for membrane association and catalysis by phosphatidylserine synthase in Escherichia coli. Science Advances, 10(51), eadq4624.
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PmtA from R. thermophilum complexed with DMPE and SAH 이미지
PmtA from R. thermophilum complexed with DMPE and SAH PDB: 8YS9 Crystal structure of Phosphatidylethanolamine N-methyltransferase from R. thermophilum complexed with DMPE and SAH Publication: Salsabila, S. D., & Kim, J. (2024). Structural insights into phosphatidylethanolamine N-methyltransferase PmtA mediating bacterial phosphatidylcholine synthesis. Science Advances, 10(40), eadr0122.
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CmoM from E. coli complexed with sinefungin and tRNA-Ser 이미지
CmoM from E. coli complexed with sinefungin and tRNA-Ser PDB: 8JOZ Crystal structure of CmoM from E. coli complexed with sinefungin and cellularly expressed tRNA Ser(2.22 Å) Publication : Jaehun Yoo, Jangmin Lee, Jungwook Kim, Structural basis for the selective methylation of 5-carboxymethoxyuridine in tRNA modification, Nucleic Acids Research, Volume 51, Issue 17, 22 September 2023, Pages 9432–9441, https://doi.org/10.1093/nar/gkad668
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MnmM from B. subtilis and S. aureus complexed with anticodon stem-loop 이미지
MnmM from B. subtilis and S. aureus complexed with anticodon stem-loop PDB: 8H1B Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A) PDB: 8H0S Crystal structure of MnmM from B. subtilis complexed with Gln-TTG anti-codon stem loop and SAM (2.90 A) PDB: 8H1A Crystal structure of MnmM from S. aureus in apo state (1.44 A) PDB: 8H0T Crystal structure of MnmM from B. subtilis complexed with SAH (1.17 A) PDB: 8H27 Crystal structure of MnmM from S. aureus complexed with SAM (2.04 A) Publication Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification Author: Gyuhyeok Cho, Jangmin Lee, and Jungwook Kim Nucleic Acids Res. 2023 Feb 10;gkad048. doi: 10.1093/nar/gkad048.
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